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Both Ozempic and Wegovy users are generally started on a dosage of 0.25mg, with Wegovy users eventually given a dosage of 2.4mg per week. Their efficacy varies from person to person, with dietary habits, physical activity and other medical conditions all playing a part, says superintendent pharmacist Carolina Goncalves from Pharmica

The results at 5mg may improve on their own as the body finishes adjusting

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Instead, reduced appetite naturally leads to lower sodium and carbohydrate intake, both of which influence how much fluid the body retains

Parr-Sturgess CA, Tinker CL, Hart CA, Brown MD, Clarke NW, Parkin ET (2012) Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signaling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells