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If you are experiencing side effects with semaglutide, trying liraglutide (a daily injection with a shorter half-life) may be easier to tolerate than once-weekly options for some patients

Triolo M, Hood DA

This adaptive response normalises glucose homeostasis but potentially reduces the glucose-lowering effect over time

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Front Endocrinol (lausanne) 10:389 Gerich JE, Lorenzi M, Bier DM, Schneider V, Tsalikian E, Karam JH et al (1975) Prevention of human diabetic ketoacidosis by somatostatin