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Exercise is the framework
14.9% mean weight loss with FDA-approved 2.4mg semaglutide over 68 weeks (directly applies to Ro-prescribed Wegovy): nejm.org/doi/full/10.1056/NEJMoa2032183 New England Journal of Medicine SURMOUNT-1 (Jastreboff et al., 2022)
In announcing the program, the health secretary, Robert F Kennedy Jr, projected the American public would collectively lose 125m pounds by this time next year
Each step up in dose brings a temporary spike in fatigue, followed by adaptation
Dehydration worsens nausea, headaches, and fatigue
Kocatrk E, Podder I, Zenclussen AC, KasperskaZajac A, Elieh-Ali-Komi D, Church MK et al (2022) Urticaria in pregnancy and lactation
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