Research shows 56% of patients on GLP-1RAs had much gastric content despite following standard fasting guidelines, while only 19% of non-users showed similar results [33]
One series that included the rostral-caudal extent of the NTS was used to detect RNA levels of Y1-R (RNAscope Probe Rn-NPY1-R-C1), GLP-1R (RNAscope Probe Rn-GLP-1R-C2), and f-Cy5-GEP44
Compounded semaglutide is significantly cheaper ($100-200/month vs
This resulted in a 2025-2035 average yearly erosion rate of around 2%, which we now believe was too benign
And this was a great conversation and I enjoyed having it, so thank you for having me
Notably, GLP-1RA differs from traditional antidiabetic drugs due to the broad distribution of GLP-1R across multiple organs, including the pancreas, central nervous system, cardiovascular system, liver, adipose tissue, and skeletal muscle