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Personalized dosing helps us get the benefits while lowering risks or side effects
Because it avoids hepatic first-pass metabolism, circulating citrulline is primarily cleared by the proximal renal tubule, where it is enzymatically converted to arginine
Patients were excluded according to the following exclusion criteria: (1) with hepatocellular carcinoma or hepatic metastases
ESA metabolites are detected in tumors of treated mice and are associated with the expression of a ferroptotic gene signature
genetic studies
Hou H, Sun D, Zhang X
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