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doi: 10.1371/journal.pone.0021827 277 ToK.CaoR.YegiazaryanA.OwensJ.NguyenT.SasaniniaK.et al
Interestingly, in patients who went on to develop PACS, there were notable reductions in the total EVs levels of the MPs Mitochondrial Open Reading Frame of the 12S rRNA-c (MOTS-c), Voltage-Dependent Anion Channel 1 (VDAC-1), and humanin, along with increased levels of Sterile Alpha and TIR Motif-Containing Protein 1 (SARM-1)
Quality of life is severely impacted despite all interventions
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