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No participants in any clinical trial developed detectable anti-AOD9604 antibodies, even after 24 weeks of continuous exposure
In addition, B12 deficiency can result in Megaloblastic Anemia, a type of anemia in which the red blood cells grow without dividing, becoming enlarged
Atrophic gastritis where the stomach lining becomes thinner
In some in-vitro studies, fibroblast cultures exposed to AHK-Cu complexes appeared to show an increase in collagen type I production, with reports of increases as high as 300% over controls
These patients are often recommended to receive 1 mg of oral vitamin B12 daily indefinitely, but intramuscular injections may be necessary if oral supplementation is insufficient Mahawar2018Langan2017