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Common symptoms The common symptoms of heartburn are: A burning sensation in the chest or upper abdomen that usually starts or worsens after meals or at night Indigestion and abdominal discomfort A sour taste in the throat and mouth Belching or the feeling of acidic food flowing up into the throat Chest discomfort that worsens when lying down or bending forward Related gastrointestinal issues As semaglutide delays digestion, heartburn can appear with related gastrointestinal (GI) side effects

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Gerstein HC, Miller ME, Byington RP, Goff DC Jr, Bigger JT, Buse JB, Cushman WC, Genuth S, Ismail-Beigi F, Grimm RH Jr

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Balb/c mice used in this study were purchased from the Laboratory Animal Center of Shanghai Lingchang Biotechnology