controls [12, 14]
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Alternatively, some patients successfully discontinue semaglutide and maintain weight through intensive lifestyle intervention: structured meal planning, consistent strength training, sleep optimization, and stress management
Under the stimulation of lactate, the METTL3/YTHDC1 axis mediates the stability of ACSL4 mRNA through m6A modification, which leads to an increase in ACSL4, inducing ROS accumulation and mitochondrial-dependent ferroptosis, thereby exacerbating lactate-induced ferroptosis in pulmonary epithelial cells[209]