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NNMT inhibition affects the methylation cycle and cellular methylation potential, which are fundamental processes in cancer cell metabolism

NNMT is a cytoplasmic enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine (SAH)

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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action AOD-9604 mimics the fat-metabolizing region of growth hormone

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