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Jazmin Aguilera: It sounds like a pretty big downside

Ran L, Chen Q, Lu X, Gao Z, Cui F, Liu X, Xue B (2023) Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells

Most studies reported reductions in itching severity, although effect sizes varied, and some studies noted mild or non-significant improvements

Are well suited for long-term, daily use

Its main physiological role is to participate in the transport of fatty acids (fats) into the cellular power plants called mitochondria , where they are subsequently used for energy production

However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)