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Indication and Usage RYBELSUS (semaglutide) tablets 7 mg or 14 mg is indicated: as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) in adults with type 2 diabetes mellitus who are at high risk for these events References: RYBELSUS [package insert]
Most clinicians prefer to start metformin first and titrate it to 1000 to 2000 mg daily over 2 to 4 weeks before adding semaglutide
Semaglutide mimics this natural hormone but is designed to last much longer in the body
Market Opportunity: Advancements in dual and triple agonist therapies acts as an opportunity for the GLP-1 Receptor Agonist market
Neither compound should be combined with other peptides without careful consideration of potential interactions
Presented for research literature review only Shahmohamadi E et al
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