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10.1016/j.bbrc.2018.05.143 Biochem
Given that cystine starvation activated the GCN2-eIF2-ATF4 axis, we evaluated the expression of several AARE-containing genes
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Meanwhile, a semiconductor polymer nanoscale PROTAC (SPNFeP) formed by nano-precipitation through sonodynamic semiconductor polymer, ferroptosis inducers, and newly synthesized proteolysis-targeting chimera (PROTAC) molecules, can deliver activated PROTAC molecules to tumor sites to degrade nicotinamide phosphoribosyltransferase (NAMPT) thereby inhibiting the infiltration of tumor MDSCs, promoting anti-tumor immunity and suppressing tumor growth (136)
Patients with these mutations may benefit from more personalized treatment strategies and close clinical monitoring to ensure optimal thyroid hormone replacement
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