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Disclosure The authors report no conflicts of interest in this work

Complementarily, metabolomics reveals the accumulation of osmolytes, soluble sugars, and organic acids that modulate nutrient uptake and redistribution, while ionomics provides a direct readout of ionic imbalances, such as K and Ca 2 depletion during drought or Na accumulation in saline soils

Metabolic changes included a reduction of the usage of muscle glycogen (i.e., its carbohydrate stores) during low-intensity exercise (consistent with an increase in lipid utilization) and streamlined glucose metabolism and mitochondrial flux during high-intensity exercise, leading to reduced anaerobic ATP production (which is what leads to lactic acid build-up in muscles)

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Typical Dosage Range Most protocols use between 600 mg and 1200 mg per session