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2022;10:e4469
[38] noted GLP-1 binds to receptors on vagal afferent neurons, which decreased postprandial pancreatic digestive enzyme secretion
Therefore, it is unlikely to cause false positives
This formulation is available as mini troches (oral tablets) rather than injectable, starting at approximately $4 per troche
A separate human study measured endogenous DSIP across normal subjects and patients with sleep apnea and narcolepsy, treating the compound as an endogenous marker rather than a confirmed therapeutic (PMID 8532601)
In clinical trials, peak weight loss on tirzepatide occurred by 9 months
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