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The goal in the research framing is a well-placed, physiological pulse, not the largest possible dose
Parrow NL, Fleming RE
Its ability to activate sirtuins, enhance DNA repair, regulate metabolism, influence fat cell metabolism in preclinical models and support mitochondrial health positions it as a compelling candidate for further investigation
Obese class III, MASLD and/or higher-risk metabolic phenotypes resistant to incretin drug effects
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In the STEP UP clinical trial, participants on the highest dose of Wegovy (7.2mg) lost an average of 20.7% of their body weight over 72 weeks 2
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