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In children receiving long-term risperidone, the ratio of Bacteroidetes to Firmicutes (two major bacterial groups in the gut) dropped significantly from 1.24 in psychiatric controls to just 0.20 in those who gained a lot of weight
Practical Neurology
doi:10.1016/0002-9610(89)90252-3
Cell 124 , 12991299
To develop heterobifunctional PROTACs recruiting the E3 ubiquitin ligases VHL or CRBN to RNF4, we used the established VHL- and CRBN-based E3 ligands and different linker moieties for proteasomal degradation of RNF4
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