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Together, certain side effects compound
Indeed, it was clearly shown that the antioxidant N-acetyl-L-cysteine (NAC) can inhibit eryptosis in vitro [116] and significantly prolong the half-life of circulating mouse erythrocytes in vivo [72] presumably by interfering with efferocytosis of eryptotic cells
However, several drugs have been approved and clinically implemented for obesity caused by other genetic mutations in the MC4R pathway, as summarized in Table 4
