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Many inflammatory chemokines are mainly produced by synovial macrophages and FLS in the joints of RA patients, whereas CX3CL1 is produced by synovial endothelial cells

When reduced forms of coenzyme Q 10 (CoQ 10 H 2 ), vitamin C (ascorbate), or glutathione (GSH) reduce oxidized -tocopherol (-TO), they themselves become oxidized (ubisemiquinone, dehydroascorbate, or GSSG)

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