VvGST4 (A12M): VvGST4 _A12M_fw, VvGST4 _A12M_rv, VvGST4 (C13S): VvGST4_ C13S_fw, VvGST4 _C13S_rv, VvGST4 (N108H): VvGST4 _N108H_fw, VvGST4 _N108H_rv (Supplementary Table 4) using pANT20 as template
Gradual introduction : Start with lower doses and increase gradually to minimise gastrointestinal upset, particularly with berberine
As individual needs may vary, I highly recommend working with a healthcare practitioner to determine optimal dosages for your condition
Stable curves may simply be monitored with regular X-rays
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Common experiences after the first injection include: Mild soreness or redness at the injection site (usually resolves within 12 days) Slight improvement in energy levels or mood No immediate noticeable change (particularly common if deficiency is severe) Rarely, mild side effects such as headache or dizziness Some patients report their urine becoming brighter or more intensely coloured following injection, which occurs because excess B12 is excreted renally