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Abbreviations ALT: Alanine aminotransferase ALP: Alkaline phosphatase AST: Aspartate aminotransferase CCSEA: Committee for Control and Supervision of Experiments on Animals CP: Cyclophosphamide ELISA: Enzyme-linked immunosorbent assay FF: Fenofibrate GGT: Gamma-glutamyl transferase GSH: Reduced glutathione H&E: Hematoxylin and eosin H 2 O 2 : Hydrogen peroxide IHC: Immunohistochemistry IL-1: Interleukin-1 IL-6: Interleukin-6 LEV: Levocabastine MDA: Malondialdehyde MT: Massons trichrome NO: Nitric oxide Nrf2: Nuclear factor erythroid 2-related factor NF-B: Nuclear factor kappa-B OH: Hydroxyl radical ROS: Reactive oxygen species SD: Standard deviation SOD: Superoxide dismutase TBARS: Thiobarbituric acid reactive substance TGF-: Transforming growth factor-beta TNF-: Tumour necrosis factor-alpha References Abdel-Wahhab KG, Mannaa FA, Ashry M, Khaled DM, Hassan LK, Gomaa HF (2021) Chenopodium quinoa ethanolic extract ameliorates cyclophosphamide -induced hepatotoxicity in male rats

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The dual function of inhibiting MMP-2/9 activity and promoting angiogenesis was achieved by cleavage of TIMPs occupying upregulated MMP-2/9 and the simultaneous release of bFGF

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