Mean monthly headache days reduced significantly in the exenatide arm ( 7.7 days) compared to the placebo arm (-1.5 days), with no significant difference between exenatide and placebo groups at 12 weeks
Even if one chooses not to take a GLP-1 to manage weight loss, adherence to a Mediterranean-style diet, adequate hydration, and resistance training combined with aerobic exercise is recommended for weight loss and preservation of muscle mass.
For example, we can expect to see: Oral agents If you have a particular product for a receptor (a non-peptide small molecule) and it can be given as a pill that makes it convenient, accessible, and less expensive to produce and ship around the country, then we can start to see the market shift significantly
GLP-1 receptor agonists carry a small increased risk of pancreatitis (Faillie et al., JAMA Internal Medicine 2014)
Go, VLW, Hofmann, AF, Summerskill, WHJ
For ideal results, we recommend one injection per month