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In the avian inner ear and zebrafish lateral line, the predominant mode of regeneration involves supporting cell division prior to conversion of one daughter cell to a sensory hair cell
Preclinical investigations indicate its role in regulating nitric oxide pathways and enhancing the expression of growth factors, which promotes the formation of new blood vessels and collagen deposition in injured tissues
Physicians who prescribe it do so entirely off-label, accepting medicolegal risk and the burden of informed consent
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