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It is prohibited at all times under the 2026 Prohibited List

Treatment of Stage III Melanoma That Cannot Be Removed By Surgery, Stage IV Melanoma, and Recurrent Melanoma Treatment of stage III melanoma that cannot be removed by surgery, stage IV melanoma, and recurrent melanoma may include: immunotherapy with pembrolizumab, nivolumab, ipilimumab, interleukin-2 (IL-2), nivolumab and relatimab, or atezolizumab, given alone or in combination targeted therapy with dabrafenib, trametinib, vemurafenib, cobimetinib, encorafenib, binimetinib, given alone or in combination oncolytic virus therapy (talimogene laherparepvec) injected into the tumor palliative therapy to relieve symptoms and improve the quality of life: chemotherapy surgery to remove lymph nodes or tumors in the lung, digestive tract, bone, or brain radiation therapy to the brain, spinal cord, or bone Learn more about these treatments in the Treatment Option Overview

Its rare and mostly avoidable by sticking to the dosing frequency I recommend

This helps you sleep through any initial nausea or flushing

Balancing blood sugar in people with insulin resistance

Labs are checked at baseline and 8-12 weeks to ensure IGF-1, fasting glucose, and lipids are in healthy ranges