tirzepatide for cardiovascular disease UC Irvine researchers project cardiac benefits from weight-loss medication Cardiovascular Outcomes with Tirzepatide Compared

The transformation is often described as exciting and rewarding watching your skin take on that rich, even bronze day by day feels truly satisfying

A two-year semaglutide study (STEP 5) in people without diabetes found an average of 15% weight loss on semaglutide

And over time, weight regain becomes more likely

Generic tirzepatide is currently only approved for type 2 diabetes, while semaglutide (as Wegovy) is FDA approved specifically for weight loss

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

43,44 In chronic stress-induced depression models, astrocytes often undergo morphological atrophy and functional asthenia, including impaired glutamate clearance, reduced neurotrophic support, and retraction of fine perisynaptic processes