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It has been investigated in clinical and research settings for its interaction with amylin receptors involved in satiety signaling and metabolic control

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A recent systematic review of GLP-1 agonist exposure found that animal studies showed risks such as fetal growth restriction and skeletal abnormalities, and due to limited human data, experts recommend stopping these medications in both pregnancy and during breastfeeding

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The Wegovy pill is semaglutide, and semaglutide has years of evidence behind it

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It's a lab-engineered peptide designed to amplify IGF-1 receptor activation beyond what endogenous IGF-1 achieves

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10.1016/S1470-2045(15)70134-8 160 GuzzettaK

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