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Patients on dual therapy with metformin HCl 1500 mg/day and rosiglitazone 4 mg/day or with metformin HCl 1500 mg/day and pioglitazone 30 mg/day (switched to rosiglitazone 4 mg/day) entered a dose-stable run-in period of 6 weeks

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Nedd4 ubiquitylates vdac2/3 to suppress erastin-induced ferroptosis in melanoma

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Similar protective effects on podocyte pyroptosis mediated by HO-1 were proved by multiple drugs, including atorvastatin, triptolide