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New persistent headaches, especially with visual symptoms (consistent with intracranial-hypertension warning in the Increlex label)

Allergic Reactions : Though rare, some people may experience severe allergic reactions to semaglutide

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Top of FormBottom of Form The Bottom Line GLP-1 is not a trend

However, some people report a complete loss of appetite As tirzepatide targets two hormones and retatrutide targets three, it may mean that tirzepatide is easier to tolerate at low doses, but more testing and data is needed