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Neuropharmacology 62 (5-6), 19161927
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CrossRef Betaine Attenuates HighFatDietInduced MetabolismAssociated Steatotic Liver Disease via the Inhibition of Ferroptosis Through the Nrf2/GPX4 Axis Xiaojun Zhai, Cheng Xiao, Chunru Yang, Zerui Ding, Dongmei Wang, Jieying Liu, Yu Miao The FASEB Journal.2025;[Epub] CrossRef Alterations in Choline Metabolism in Non-Obese Individuals with Insulin Resistance and Type 2 Diabetes Mellitus Haya Al-Sulaiti, Najeha Anwardeen, Sara S
2.11 Reduced glutathione quantification GSH quantification was performed using established Ellman Assay, where GSH reacts specifically with the Ellmans reagent (DTNB) to yield 2-nitro-5-mercapto-benzoic acid (TNB), which produces a concentration-dependent yellow chromophore quantifiable by spectrophotometry ( 2.12 Measurement of myeloperoxidase activity Neutrophils are primary responders to inflammation, which can be studied by quantifying the activity of myeloperoxidase, an enzyme abundantly present in their granules ( 2.13 Histopathological examination Liver and pancreatic tissues were duly fixed in formalin (10%) solution to preserve structural integrity and prevent decomposition
Additionally, multi-modal theranostic nanoplatforms integrating imaging (MRI/fluorescence) and therapy will enable real-time monitoring of drug delivery and efficacy, facilitating adaptive treatment adjustments
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