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2.2 Mood-stabilizers 2.2.1 Lithium The role of PKC in the pathophysiology of bipolar disorder was suggested in 1994 by Manji and colleagues after observing that chronic lithium use has PKC-dependent transcriptional and posttranscriptional effects involving long-term neuroplasticity and cellular response
Currently, no medications are approved for obesity treatment in children younger than 12 years, but a randomized controlled trial of 82 patients 6 to 12 years of age found that liraglutide resulted in an estimated BMI reduction of 7% compared with placebo, suggesting potential future applications
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But polyunsaturated was kind of better in a dose response
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