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Drug Metab Dispos 30(8):861868

Occasionally, a person may say that the affected leg feels heavy, which might indicate some level of weakness

The answer isn't a simple yes or no

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However, there are situations when you should seek urgent medical attention or go to the Emergency Room, particularly if you experience any of the following: Severe Abdominal Pain: If your stomach becomes swollen, distended, or if you experience sharp, persistent pain, it could indicate a more serious issue, such as a bowel obstruction