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493 Mutations in LIG3 , the only mtDNA ligase essential for mtDNA replication and repair, also affect mtDNA maintenance and have been reported in patients with MNGIE, leading to mtDNA depletion
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2 In recent years, growing concerns have arisen regarding the potential impact of glucose-lowering medications on muscle health, generating significant clinical debate
Additionally, it includes beneficial compounds like L-Taurine, MIC (Methionine, Inositol, Choline), and Glutathione, a potent antioxidant
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Cells were washed twice with PBS, trypsinized, and then incubated with 500 l HBSS (C14175500BT, Gibco, United States) supplemented with 2 M C11-BODIPY 581/591 (D3861, Thermo Fisher, United States) at 37C for 15 min
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