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High doses of estradiol also significantly decrease the amount of insulin receptors and the insulin receptor substrate 1 (IRS-1) levels in muscle and adipose tissue in vitro (174)
He was sharing a patient story about how taking a GLP-1 gave them relief from the food noise, and I remember thinking, Thats exactly what Ive been fighting my entire life! I had already lost 100 pounds, twice , through diet and exercise, but I was still struggling with the last 40 pounds I wanted to lose to reach a healthier weight for my body
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