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The medication is still in phase 3 clinical trials for weight reduction and hasnt been approved by any regulatory authority, including the MHRA (Medicines and Healthcare Products Regulatory Agency) in the UK
Most patients notice reduced shedding and a healthier-looking scalp within 2 to 4 weeks
Important safety considerations include a boxed warning for medullary thyroid carcinoma risk (contraindicated in patients with MEN2 or family history of MTC), pancreatitis risk, gallbladder disease, and potential for dehydration
Some may experience mild nausea or upset stomach
Those taking SGLT2 inhibitors alongside GLP-1/GIP medications face additional risks, including increased urination and potential for euglycemic diabetic ketoacidosis if severely dehydrated
The present study adds oxidative stress, as indexed by GSH depletion, as another dimension of thalamic involvement in migraine
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