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MASH resolution without worsening of fibrosis: 2.4 mg dose: 47% of participants (vs 14% placebo) 4.8 mg dose: 62% of participants (vs 14% placebo) 6.0 mg dose: 43% of participants (vs 14% placebo) Liver fat reduction of at least 30%: 2.4 mg dose: 63% of participants 4.8 mg dose: 67% of participants 6.0 mg dose: 57% of participants Placebo: 14% of participants Fibrosis improvement by at least one stage: Survodutide groups: 34-36% Placebo: 22% The percentage change from baseline in liver fat content after 48 weeks was a staggering 62% reduction in the 6.0 mg group, compared to just 5.7% in the placebo group
Animal studies have linked it to a slowed progression of diabetes, obesity, and IBD
HCPCS Coding for GLP-1 Medications When GLP-1 drugs are administered in a clinical setting (not retail pharmacy), coders may bill using HCPCS J-codes
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Serious Adverse Events Serious adverse events were relatively uncommon and did not show a clear dose-response signal
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