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In addition to neural connections, the central clock system also synchronizes the circadian rhythms of the peripheral clock system through hormones or factors, such as arginine vasopressin (AVP) and tumor necrosis factor (TNF) ( FIGURE 1 The clock system mainly regulates metabolism in the following three ways
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Dose limitation: There may be a practical ceiling on how much peptide you can deliver effectively via a nasal spray without irritation or escape (e.g., dripping into the throat)
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