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The PIONEER 5 study was a multicenter, double-blind, randomized, placebo-controlled, phase 3a trial where 324 participants, age 18yrs, with type 2 diabetes, HbA1C 7.0-9.0% and moderate renal impairment (eGFR 30-59 mL/min/1.732), were randomly assigned to receive either once-daily oral semaglutide on an empty stomach with up to half a glass of water and 30min before any food/beverage/medication, or placebo for 26 weeks with a follow up period of 5 weeks, with their standard glucose-lowering medication
Results A total of 648,070 adult patients with T2D and NAFLD were identified, and patients were categorized into three different comparison groups based on their drug of interest
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(Tip): Add a serving to sparkling water for a delicious anytime drink
Photo Credit: Jessica Kielman, Baldwin Publishing 120 mins Simple, flavorful, and versatile, this roasted chicken is a reliable source of protein thats easy to make and feeds the whole family
(b) uncontrolled hypertension, which is a systolic blood pressure above 140 mm Hg or diastolic blood pressure above 90 mm Hg while on two antihypertensive medications
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