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Semaglutide is a modified molecule our bodies make, called a GLP-1 analog
A commonly recommended pace for sustainable weight loss is no more than 1-2 pounds per week , though this varies by person
GLP-1 medications have a well-established safety profile from large-scale clinical trials
Nutr Clin Pract
Demand and supply pressures: High demand for GLP-1 medicines has already caused significant supply shortages in the UK, which have been the subject of NHS England and MHRA National Patient Safety Alerts
In general, GLP-1 is thought to have two effects, one exerted via the central nervous system and the other exerted via local receptors in the periphery
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