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The extremely long half-life (~12 days) raises additional concerns about compound accumulation with chronic daily dosing

Injection site reactions

The authors also reported that levels returned to baseline after a one-month washout period, and that natural killer cytotoxicity increased more than twofold in the high-dose group versus placebo (P less than 0.05) at 3 months

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Presented for research literature review only Younger JB et al