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This synergy is one of the main reasons why the no-DAC version is preferred over the DAC version in most research and clinical protocols that aim to maintain natural signaling patterns

[2] It is one of the few peptides that has crossed the boundary from laboratory research into widespread commercial skincare products, appearing in serums, creams, and post-procedure treatments marketed for anti-aging effects

2 Materials and methods 2.1 Experimental animals Male C57BL/6J mice [specific-pathogen-free (SPF) grade], aged 810 weeks and weighing 2025 g, were obtained from the Laboratory Animal Center of Ningxia Medical University

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