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Tryptophan oxidation is the degradation route most commonly detected by RP-HPLC in stored melanocortin analogues, with histidine a secondary site of concern, and freeze-thaw cycling accelerates both aggregation and oxidative degradation
In this study, we designed a peptide inhibitor based on the p53 transactivation domain (TAD) sequence and investigated its binding interface at the atomic level using NMR spectroscopy
This product is intended exclusively for laboratory investigation of metabolic regulation mechanisms and is offered as a research chemical for scientific use only
*Based on a clinical study of 18 panelists.
Epilepsia 61 , 23402364 (2020)
Stephanie Ishack,PhD and Shari R
