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Its also the primary treatment, used intravenously, for people hospitalized with acetaminophen poisoning which affects more than 70,000 people per year
Miralax (polyethylene glycol) is safe for long-term use and effective when other methods fall short
Many people find switching to gentler brews or drinking coffee with food reduces this effect significantly
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One 2025 review in Osteoporosis International found that GLP-1s enhanced bone remodeling and also decreased bone mineral density over time, leaving the authors to raise questions over the possibility of future bone fractures
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