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Nature 534 , 710713 (2016)
Lipotropic (lipo) shots are injectable formulations marketed primarily through private clinics and wellness centres, containing a combination of compounds purported to enhance fat metabolism
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Glucuronidation (50-60%) - SAFE Primary detoxification pathway in adults Makes acetaminophen water-soluble for excretion INCREASES during pregnancy but cannot compensate for other pathway changes Severely underdeveloped in fetuses/newborns 2
xCT deficiency induces autophagy via endoplasmic reticulum stress activated p38-mitogen-activated protein kinase and mTOR in sut melanocytes
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