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Older research on rats suggests that it works by activating the melanocortin 4 receptor (MC4R), which then stimulates the cavernous nerve in the penis, which helps men get an erection (8)
More research is needed to understand the implications of its prolonged use
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In skeletal muscle, it inhibits muscle atrophy, preserves muscle strength, and enhances exercise endurance, as well as increases glucose uptake and storage in myocytes [41]
The 12mg dose represents the optimal balance point identified in clinical trials