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Protein: 42g
doi:10.1172/JCI60016
The effects compound as the dose escalates
MPNSTs often appear as large, heterogeneously enhancing, and poorly defined soft-tissue masses on MRI
Practical management considerations include: Dose review: If the heart rate increase is dose-dependent and symptomatic, reducing the dose or slowing the titration schedule where permitted by the trial protocol may help mitigate the effect whilst preserving therapeutic benefit
Villanueva-Pecarrillo ML, Mrquez L, Gonzlez N, Daz-Miguel M, Valverde I
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