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Morphologically, no significant abnormalities were seen in the testes and spermatozoa of mice after SNGPX4 KO ( 2.5 GPX5 Glutathione peroxidase 5 (GPX5), an epididymis-specifically expressed selenium-free antioxidant enzyme, was first isolated and identified in the epididymal tissues of mice (Taylor et al., 2013)

13 Nonetheless, localized use of skin bleaching agents may be of benefit to pigmentary disorders, thus its important to fully evaluate the safety and efficacy of topical glutathione in this context

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