In this episode, Don and Steve dig into the evidence behind the most talked-about risks of GLP-1 agonists , separating clinical truth from rumors and headlines
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This ensures correct dosing, proper screening for contraindications, and monitoring of side effects
Quality, long-term data on 5-amino-1MQ is lacking
Recent analysis by the American Academy of Actuaries suggested that the high cost of these medications, combined with the need for long-term use, could place upward pressure on 2025 health insurance premiums, particularly as more patients met clinical criteria for covered diagnoses
Compare that to the STEP 1 extension data, where participants regained 11.6 percentage points within 52 weeks of stopping semaglutide without any structured dietary intervention