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The risk of DKA does not appear to be elevated with GLP-1 drugs in T1D a meaningful distinction from SGLT2 inhibitors

If you take levothyroxine and Rybelsus, this is especially important to mention due to potential increased levothyroxine exposure

Retatrutide binds to the GLP-1, GIP, and glucagon receptors at the same time, triggering a chain of effects: GLP-1 (Glucagon-Like Peptide-1) receptor: suppresses appetite and slows digestion

Dosage and duration of use have not been established

Immune activation Your immune system ramps up inflammatory signaling to help clear debris (source)