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A compound that is clean enough for a binding assay is not automatically clean enough for a quantitative cell-based readout where a co-eluting impurity could carry activity of its own
1990 Feb;11(1):1-14
Less common but clinically significant adverse effects include vitamin B12 deficiency with long-term use
How does SNAC aid the formula
Hasanuzzaman, M
Study Assessments Serum HCV RNA was measured by means of the COBAS AmpliPrep/COBAS TaqMan HCV Quantitative Test, version 2.0 (Roche Molecular Systems), with a lower limit of quantification of 15 IU per milliliter
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