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10.1016/S0092-8674(00)81405-1 7 BaiH.LanJ

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In the latter conformation, the rAmy bypass motif becomes disordered, enabling the receptor ECD to adopt a position similar to CT-bound CTR or AMYR complexes 15

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However, its receptor residence time the duration the ligand remains bound is relatively short, on the order of 36 minutes, in contrast to salmon calcitonins residence time of approximately 4560 minutes